Dylan McDermott and Shiva Rose, his wife of almost 12 years, have separated.

McDermott's rep confirmed the news to PEOPLE.  The couple has been married since 1995 and have two daughters who are 11 and 2-years-old.

As PEOPLE recalls, 

In a 2001 interview with Diane Sawyer, McDermott says he saw Shiva in a coffee shop and was instantly smitten. "I was in love with her right away," he said. "For her, it was a little longer, you know, a couple of years. But for me, it was right away. I guess it was grace."

Both McDermott and Rose are actors.  He is on the new ABC drama Big Shots alongside Michael Vartan, Joshua Molina and Christopher Titus. She recently starred in the romantic comedy David and Layla opposite David Moscow.